Best price vacation rentals in Seneca, SC, USA • 135 Listings
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Seneca, SC, USA Vacation Rentals | 

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United States South Carolina West Union vacation rental compare prices direct by owner 23615691
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5.0 (24)
Cane Creek Retreat on Lake Keowee!
Up to 14 guests
Vrbo$1,451
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United States South Carolina Seneca vacation rental compare prices direct by owner 29152976
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5.0 (5)
Cozy Home on Lake Hartwell!
Up to 6 guests
Vrbo$402
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United States South Carolina Seneca vacation rental compare prices direct by owner 33562152
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5.0 (5)
Kate's Kayak Cove on Lake Keowee!
Up to 10 guests
Vrbo$614
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United States South Carolina West Union vacation rental compare prices direct by owner 28118599
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5.0 (14)
Keowee Cove Retreat on Lake Keowee!
Up to 16 guests
Vrbo$1,545
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United States South Carolina Seneca vacation rental compare prices direct by owner 23678275
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4.9 (9)
Keowee Hideout at Lake Keowee
Up to 8 guests
Vrbo$525
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Airbnb
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United States South Carolina Seneca vacation rental compare prices direct by owner 33366656
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4.7 (25)
Shoreline Chalet on Lake Keowee with hot tub!
Up to 13 guests
Vrbo$1,018
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United States South Carolina Seneca vacation rental compare prices direct by owner 36848888
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4.0 (2)
Serenity Bay on Lake Keowee!
Up to 10 guests
Vrbo$530
Verified Host
Airbnb
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United States South Carolina Seneca vacation rental compare prices direct by owner 36392850
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0.0 (0)
Valley Echoes on Lake Hartwell!
Up to 12 guests
Verified Host
Airbnb
United States South Carolina Seneca vacation rental compare prices direct by owner 37524893
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0.0 (0)
Pre-Revolutionary War Cabin on Lake Hartwell
Up to 6 guests
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Airbnb

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United States South Carolina Walhalla vacation rental compare prices direct by owner 11447377
5.0 (46)
LOFTS OVER MAIN ~ Walhalla Studio
Up to 2 guests
Vrbo$175
Airbnb
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United States South Carolina Seneca vacation rental compare prices direct by owner 28516440
5.0 (6)
4 BR- Lakefront and Mountain View home- Close to Clemson
Up to 10 guests
Vrbo$697
Airbnb
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 181271
4.8 (69)
Lakefront Keowee Cabin 14 mi. from Clemson Hot Tub
Up to 12 guests
Vrbo$758
Airbnb
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 29502643
4.7 (9)
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
Up to 10 guests
Vrbo$525
Airbnb
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United States South Carolina Seneca vacation rental compare prices direct by owner 362534
5.0 (69)
Lakefront home with private beach & unbelievable sunsets on Lake Keowee
Up to 8 guests
Vrbo$470
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 422390
5.0 (38)
Lake Keowee Condo with Great Views! Near Clemson, Marina, Hiking, Waterfalls!
Up to 6 guests
Vrbo$175
Average Nightly Rate
United States South Carolina West Union vacation rental compare prices direct by owner 474968
5.0 (84)
Serene LAKEFRONT Retreat ON Lake Keowee near Clemson, SC
Up to 10 guests
Vrbo$341
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 477261
5.0 (118)
20 Minutes to Clemson - Remodeled 4 BR/3 BA Waterfront
Up to 10 guests
Vrbo$426
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 489872
5.0 (99)
500 FT OF DEEP WATER FRONTAGE ON THE BEAUTIFUL EMRALD COLOR WATER OF LAKE KEOWEE
Up to 10 guests
Vrbo$677
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 491345
5.0 (31)
The Cutt, Relaxing, private, lake front paradise on stunning Lake Keowee in SC.
Up to 12 guests
Vrbo$370
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 495402
5.0 (175)
Easy access lake front W/ beach and boat ramp, waterfront patio, screened porch
Up to 14 guests
Vrbo$459
Average Nightly Rate
United States South Carolina West Union vacation rental compare prices direct by owner 540908
5.0 (100)
Gorgeous Estate w/180° views of the lake and 300+ ft of waterfront!
Up to 15 guests
Vrbo$1,530
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 587808
5.0 (46)
Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson
Up to 10 guests
Vrbo$521
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 598351
5.0 (141)
Pristine views from Lakefront Home
Up to 13 guests
Vrbo$537
Average Nightly Rate
United States South Carolina West Union vacation rental compare prices direct by owner 855439
5.0 (88)
Lake Keowee Waterfront Retreat! We call it The Hideaway!
Up to 8 guests
Vrbo$384
Average Nightly Rate
United States South Carolina Seneca vacation rental compare prices direct by owner 926905
5.0 (144)
Spectacular lake home with dock and fire pit- room for all - good pets ok-
Up to 13 guests
Vrbo$468
Average Nightly Rate
  1. United States
  2. South Carolina
  3. Seneca Vacation Rental Price Comparison

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